Published October 28, 2005
| Supplemental Material
Journal Article
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Stem-Cell Homeostasis and Growth Dynamics Can Be Uncoupled in the Arabidopsis Shoot Apex
Chicago
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Abstract
The shoot apical meristem (SAM) is a collection of stem cells that resides at the tip of each shoot and provides the cells of the shoot. It is divided into functional regions. The central zone (CZ) at the tip of the meristem is the domain of expression of the CLAVATA3 (CLV3) gene, encoding a putative ligand for a transmembrane receptor kinase, CLAVATA1, active in cells of the rib meristem (RM), located just below the CZ. We show here that CLV3 restricts its own domain of expression (the CZ) by preventing differentiation of peripheral zone cells (PZ), which surround the CZ, into CZ cells and restricts overall SAM size by a separate, long-range effect on cell division rate.
Additional Information
© 2005 American Association for the Advancement of Science. 17 June 2005; Accepted 26 September 2005; Published online 6 October 2005. We thank C.-F. Chuang, I. Moore, R. Simon, and D. Ehrhardt for DNA constructs and members of the Meyerowitz laboratory for comments on the manuscript. G.V.R. was a fellow of the Jane Coffin Childs memorial fund for medical research, and this work was supported by U.S. National Science Foundation grant IOB-0211670.Attached Files
Supplemental Material - Reddy.SOM.pdf
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Additional details
- Eprint ID
- 52065
- DOI
- 10.1126/science.1116261
- Resolver ID
- CaltechAUTHORS:20141121-153340056
- Jane Coffin Childs Memorial Fund for Medical Research
- NSF
- IOB-0211670
- Created
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2014-11-22Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field