Published September 26, 2002
| public
Journal Article
Microfluidic Large-Scale Integration
Abstract
We developed high-density microfluidic chips that contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large-scale integration. A key component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns that exponentially increases the processing power of a network by allowing complex fluid manipulations with a minimal number of inputs. We used these integrated microfluidic networks to construct the microfluidic analog of a comparator array and a microfluidic memory storage device whose behavior resembles random-access memory.
Additional Information
© 2002 American Association for the Advancement of Science. 5 August 2002; accepted 17 September 2002; published online 26 September 2002. We thank M. Enzelberger, C. Hansen, M. Adams, and M. Unger for helpful discussions. Supported in part by Army Research Office grant DAAD19-00-1-0392 and by the DARPA Bioflips program.Additional details
- Eprint ID
- 51891
- DOI
- 10.1126/science.1076996
- Resolver ID
- CaltechAUTHORS:20141118-095328959
- DAAD19-00-1-0392
- Army Research Office (ARO)
- Defense Advanced Research Projects Agency (DARPA)
- Created
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2014-11-18Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field