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Published June 2, 2014 | public
Journal Article

The uncommon roles of common gene regulatory factors in the genomes of differentiating cells

Abstract

Viewed through the lens of comparative regulatory mechanisms in developmental processes, the article of Calero‐Nieto et al (2014, this issue) is of particular interest. This work uncovers the causal combinatorial subtleties of the distinct enhancer occupancy profiles displayed by ten different transcription factors, which are expressed in common in two hematopoietic cell types, a stem cell‐like precursor and primary mast cells.

Additional Information

© 2014 The Authors. Published 30.04.2014. It is my pleasure to acknowledge most useful discussions with Ellen Rothenberg and Isabelle Peter on the subject of this commentary. The author declares that he has no conflict of interest.

Additional details

Created:
August 20, 2023
Modified:
October 26, 2023