0.5 gigapixel microscopy using a flatbed scanner
- Creators
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Zheng, Guoan
- Ou, Xiaoze
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Yang, Changhuei
Abstract
The capability to perform high-resolution, wide field-of-view (FOV) microscopy imaging is highly sought after in biomedical applications. In this paper, we report a wide FOV microscopy system that uses a closed-circuit-television (CCTV) lens for image relay and a flatbed scanner for data acquisition. We show that such an imaging system is capable of capturing a 10 mm × 7.5 mm FOV image with 0.78 µm resolution, resulting in more than 0.5 billion pixels across the entire image. The resolution and field curve of the proposed system were characterized by imaging a USAF resolution target and a hole-array target. To demonstrate its application, 0.5 gigapixel images of histology slides were acquired using this system.
Additional Information
© 2013 Optical Society of America. Received 18 Jul 2013; revised 10 Nov 2013; accepted 24 Nov 2013; published 2 Dec 2013. We acknowledge the funding support from the United States Department of Defense under grant W81XWH-09-1-0051. The scheme of this work was first presented at CLEO 2012 [22].Errata
Xiaoze Ou, Guoan Zheng, and Changhuei Yang, "0.5 gigapixel microscopy using a flatbed scanner: erratum," Biomed. Opt. Express 7, 646-647 (2016) https://www.osapublishing.org/boe/abstract.cfm?uri=boe-7-2-646Attached Files
Published - boe-5-1-1.pdf
Submitted - 1209.4045.pdf
Erratum - boe-7-2-646.pdf
Files
Additional details
- Alternative title
- Gigapixel microscopy using a flatbed scanner
- PMCID
- PMC3891323
- Eprint ID
- 43624
- Resolver ID
- CaltechAUTHORS:20140203-113756615
- W81XWH-09-1-0051
- Department of Defense
- Created
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2014-02-03Created from EPrint's datestamp field
- Updated
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2023-06-01Created from EPrint's last_modified field