Published December 20, 2013
| Accepted Version
Journal Article
Open
Recent Developments in the Catalytic, Asymmetric Construction of Pyrroloindolines Bearing All-Carbon Quaternary Stereocenters
- Creators
- Repka, Lindsay M.
- Reisman, Sarah E.
Abstract
Pyrroloindoline alkaloids constitute a large family of natural products that has inspired the development of an impressive array of new reactions to prepare the key heterocyclic motif. This synopsis will address catalytic, asymmetric reactions developed to synthesize pyrroloindolines bearing C3a all-carbon quaternary stereocenters. The methods described herein include both transition-metal-catalyzed and organocatalyzed reactions that have been demonstrated to be suitable for the synthesis of the pyrroloindoline framework.
Additional Information
© 2013 American Chemical Society. Received: August 15, 2013. Publication Date: December 2, 2013. We thank the California Institute of Technology, the NIH (NIGMS RGM097582A), the Baxter Foundation, Amgen, Boehringer Ingelheim, and the donors of the ACS Petroleum Research Foundation for providing financial support for our research efforts in this field. S.E.R. is a fellow of the Alfred P. Sloan Foundation, a Camille Dreyfus Teacher−Scholar, and an American Cancer Society Research Scholar. L.M.R was supported by a fellowship from the ACS Division of Organic Chemistry sponsored by Genentech.Attached Files
Accepted Version - nihms545893.pdf
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Additional details
- PMCID
- PMC3905788
- Eprint ID
- 42921
- DOI
- 10.1021/jo4017953
- Resolver ID
- CaltechAUTHORS:20131210-103918595
- Caltech
- RGM097582A
- NIH
- Baxter Foundation
- Amgen
- Boehringer Ingelheim
- American Chemical Society Petroleum Research Fund
- Alfred P. Sloan Foundation
- Camille and Henry Dreyfus Foundation
- American Cancer Society
- American Chemical Society Division of Organic Chemistry
- Genentech
- Created
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2013-12-11Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field