Published September 15, 2003 | public
Journal Article

Integrated microfluidic systems

An error occurred while generating the citation.

Abstract

Microchips: Multistep reactions may be catalyzed by enzymes immobilized on microbeads trapped inside microfluidic channels. Large integrated microfluidic circuits can be created by using multilayer soft lithography in poly(dimethylsiloxane). These circuits (see schematic representation) can be used to perform hundreds of different reactions simultaneously, and can be applied to a range of problems, from enzymatic assays to crystallization of proteins.

Additional Information

Copyright © 2003 WILEY-VCH. Original figures were generously provided by Prof. Richard Crooks and by Prof. Stephen Quake. Support by ONR is gratefully acknowledged.

Additional details

Created:
August 19, 2023
Modified:
October 24, 2023