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Published November 2012 | Accepted Version
Journal Article Open

The social brain in psychiatric and neurological disorders

Abstract

Psychiatric and neurological disorders have historically provided key insights into the structure-function relationships that subserve human social cognition and behavior, informing the concept of the 'social brain'. In this review, we take stock of the current status of this concept, retaining a focus on disorders that impact social behavior. We discuss how the social brain, social cognition, and social behavior are interdependent, and emphasize the important role of development and compensation. We suggest that the social brain, and its dysfunction and recovery, must be understood not in terms of specific structures, but rather in terms of their interaction in large-scale networks.

Additional Information

© 2012 Elsevier Ltd. We thank Jed Elison, John Constantino, Bob Spunt, and three anonymous reviewers for comments. Supported by grants from the NIMH to R.A. (R01MH080721; P50MH094258) and D.P.K. (K99 MH094409).

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