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Published October 15, 2012 | Supplemental Material
Journal Article Open

Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth

Abstract

Despite differences in the crystal structures of ice and nucleosides, antifreeze polypeptides (AFPs) have been demonstrated to inhibit nucleation of 5-methyluridine, cytidine, and inosine and modify the crystal growth of the nucleosides efficiently. The molecular recognition repertoire of AFPs has been expanded to non-ice-like crystalline solids.

Additional Information

© 2012 Royal Society of Chemistry. Received 28 Aug 2012, Accepted 15 Oct 2012; first published on the web 15 Oct 2012. The authors thank Prof. John Duman at University of Notre Dame for cDNA of DAFP-1; Dr Michael Day and Mr Larry Henling for X-ray crystallographic structural determination and Prof. Mark Davis and Mr Mark Deimund for PXRD instrument at California Institute of Technology. XW acknowledges support by NIH (GM086249) and Research Corporation (CC10492).

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Supplemental Material - c2cc36264c.txt

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August 19, 2023
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