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Published October 2012 | public
Journal Article Metadata-only

Detection of circulating tumor cells in advanced renal cell carcinoma patients using microfilter-based capture

Mittal, K.
Williams, A.
Rawal, S.
Ao, Z.
Lu, B.
Torres-Munoz, J.
Borden, E.
O'Malley, M.
Woodney, L.
Zheng, S.
Datar, R.
Tai, Y.-C. ORCID icon
Cote, R.
Rini, B.
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Abstract

Circulating tumor cells (CTCs) have generated considerable interest as predictive and prognostic biomarkers in solid tumors. While the current FDA approved technology utilizes epithelial cell adhesion molecule (EpCAM) expression for CTC detection, renal cell carcinoma (RCC) cells do not consistently express EpCAM. Based on size differences between larger epithelial tumor cells and smaller nontumor blood cells, CTCs can also be detected using a parylene-based microfilter device.

Additional Information

© 2012 The Authors. BJU International © 2012 BJU International. Article first published online: 10 Oct. 2012.

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October 20, 2023