Published December 2010
| public
Conference Paper
Polymer nanoparticle-based cancer therapeutics: from concept to clinic
- Creators
-
Davis, M. E.
Chicago
Abstract
Nanoparticle-based therapeutics contg. either small mol. anti-cancer agents (IT-101; entered Phase II) or siRNA (CALAA-01; in Phase I) are described. The key component in each nanoparticle is a cyclodextrin-contg. polymer that endows it with multifunctional behavior. Relationships between nanoparticle design and function in animal models are illustrated. Results from clin. trials are presented so show how nanoparticle-based therapeutics can provide interesting behavior in humans.
Additional Information
© 2012 American Chemical Society.Additional details
- Eprint ID
- 33240
- Resolver ID
- CaltechAUTHORS:20120815-152834973
- Created
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2012-08-15Created from EPrint's datestamp field
- Updated
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2020-03-09Created from EPrint's last_modified field