Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published August 10, 2012 | public
Journal Article

CMOS Neurotransmitter Microarray: 96-Channel Integrated Potentiostat With On-Die Microsensors

Abstract

A 8 × 12 array of integrated potentiostats for on-CMOS neurotransmitter imaging is presented. Each potentiostat channel measures bidirectional redox currents proportional to the concentration of a neurochemical. By combining the current-to-frequency and the single-slope analog-to-digital converter (ADC) architectures a total linear dynamic range of 95 dB is achieved. A 3.8 mm × 3.1 mm prototype fabricated in a 0.35 μm standard CMOS technology was integrated with flat and 3D on-die gold microelectrodes and an on-chip microfluidic network. It is experimentally validated in in-situ recording of neurotransmitter dopamine.

Additional Information

© 2012 IEEE. Manuscript received December 10, 2011; revised March 08, 2012; accepted May 07, 2012. This work was supported by National Sciences and Engineering Research Council of Canada (NSERC). This paper was recommended by Associate Editor T. Constandinou. The authors would like to thank Canadian Microelectronics Corporation (CMC) for providing the fabrication services and microsystem integration services.

Additional details

Created:
August 22, 2023
Modified:
October 18, 2023