Published June 1, 2012
| Published
Journal Article
Open
Development and evolution of the neural crest: An overview
Chicago
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Abstract
The neural crest is a multipotent and migratory cell type that forms transiently in the developing vertebrate embryo. These cells emerge from the central nervous system, migrate extensively and give rise to diverse cell lineages including melanocytes, craniofacial cartilage and bone, peripheral and enteric neurons and glia, and smooth muscle. A vertebrate innovation, the gene regulatory network underlying neural crest formation appears to be highly conserved, even to the base of vertebrates. Here, we present an overview of important concepts in the neural crest field dating from its discovery 150 years ago to open questions that will motivate future research.
Additional Information
© 2012 Elsevier Inc. Available online 2 January 2012. We would like to acknowledge Les Treilles Foundation, whose generous support and wonderful atmosphere provided the participants of our Neural Crest study group with an environment that stimulated discussion and promoted fruitful interactions. We are particularly grateful to Mme. Catherine Bachy, whose organizational assistance greatly contributed to the success of our endeavor.Attached Files
Published - Bronner2012p18600Dev_Biol.pdf
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Bronner2012p18600Dev_Biol.pdf
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Additional details
- PMCID
- PMC3351559
- Eprint ID
- 32034
- Resolver ID
- CaltechAUTHORS:20120622-101407248
- Created
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2012-06-27Created from EPrint's datestamp field
- Updated
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2021-11-09Created from EPrint's last_modified field