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Published March 15, 2011 | public
Journal Article

piRNAs Meet Mitochondria

Abstract

zuc/MitoPLD encodes a conserved enzyme that localizes to mitochondria and hydrolyzes the mitochondria-specific lipid cardiolipin. Surprisingly, zuc/MitoPLD activity is required for Piwi-interacting RNA (piRNA)-mediated silencing of transposable elements in fly and mouse germlines, suggesting that signaling from mitochondria influences the piRNA pathway.

Additional Information

© 2011 Elsevier Inc. Available online 14 March 2011.

Additional details

Created:
August 19, 2023
Modified:
October 23, 2023