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Published August 2006 | Published
Book Section - Chapter Open

Estimation of elastic and viscous properties of the left ventricle based on annulus plane harmonic behavior

Abstract

Assessment of left ventricular (LV) function with an emphasis on contractility has been a challenge in cardiac mechanics during the recent decades. The LV function is usually described by the LV pressurevolume (P-V) diagram. The standard P-V diagrams are easy to interpret but difficult to obtain and require invasive instrumentation for measuring the corresponding volume and pressure data. In the present study, we introduce a technique that can estimate the viscoelastic properties of the LV based on harmonic behavior of the ventricular chamber and it can be applied non-invasively as well. The estimation technique is based on modeling the actual long axis displacement of the mitral annulus plane toward the cardiac base as a linear damped oscillator with time-varying coefficients. The time-varying parameters of the model were estimated by a standard Recursive Linear Least Squares (RLLS) technique. LV stiffness at end-systole and end diastole was in the range of 61.86-136.00 dyne/g.cm and 1.25-21.02 dyne/g.cm, respectively. The only input used in this model was the long axis displacement of the annulus plane, which can also be obtained non-invasively using tissue Doppler or MR imaging.

Additional Information

© 2006 IEEE. Manuscript received December 15, 2005. This work was supported in part by NIH grants HL-63954, HL-71137, HL-73021 and HL-76560.

Attached Files

Published - Kheradvar2006p88782006_28Th_Annual_International_Conference_Of_The_Ieee_Engineering_In_Medicine_And_Biology_Society_Vols_1-15.pdf

Files

Kheradvar2006p88782006_28Th_Annual_International_Conference_Of_The_Ieee_Engineering_In_Medicine_And_Biology_Society_Vols_1-15.pdf

Additional details

Created:
August 19, 2023
Modified:
March 5, 2024