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Published October 25, 2010 | public
Journal Article

Reprogramming Directional Cell Motility by Tuning Micropattern Features and Cellular Signals

Abstract

Simple geometrical constraints of micropatterned substrates can be used to manipulate the direction and directional persistence of motile cells (scale bar: 20 μm). Modulation of the directional bias is demonstrated by altering pattern parameters and signal pathways.

Additional Information

© 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received: May 3, 2010; Revised: May 20, 2010; Published online: September 3, 2010. This research was funded by the NSF Center for Science and Engineering of Materials at Caltech. We also gratefully acknowledge the technical support and infrastructure provided by the Kavli Nanoscience Institute.

Additional details

Created:
August 22, 2023
Modified:
October 20, 2023