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Published July 12, 2010 | public
Journal Article

Three-Dimensional Structure and Thermal Stability Studies of DNA Nanostructures by Energy Transfer Spectroscopy

Abstract

Structural changes and stability of DNA nanoarchitectures including Y-shaped DNA (see picture), dendrimer-like DNA, and DNA hydrogels are investigated. The results demonstrate the feasibility and flexibility of FRET and NSET (Förster resonance/ nanometal surface- energy transfer) in determining difficult-to-obtain 3D structures and characterizing the thermal responses of DNA nanoarchitectures in real time.

Additional Information

© 2010 Wiley-VCH Verlag GmbH& Co. KGaA, Weinheim. Article first published online: 5 May 2010. This work was partially supported by the USDA NRI and the NSF CAREER award, and performed in part at the Nanobiotechnology Center and Cornell Center for Materials Research, which are supported by the National Science Foundation, Cornell University, and industrial affiliates.

Additional details

Created:
August 22, 2023
Modified:
October 20, 2023