Published 2010
| Published
Book Section - Chapter
Open
Parylene membrane slot filter for the capture, analysis and culture of viable circulating tumor cells
Chicago
An error occurred while generating the citation.
Abstract
This paper presents a method of capturing viable circulating tumor cells (CTC) from human whole blood using constant-pressure-driven filtration through a specially designed parylene-C membrane "slot" filter. More than 90% viable cancer cells could be recovered from whole blood using the slot filter, with minimal non-cancer blood cells left on the filter. The feasibility of the telomerase activity measurement of a single cancer cell taken from the filter after capture was proven. The on-filter and off-filter cultures of the captured cancer cells were also demonstrated.
Additional Information
© 2010 IEEE. The funding of this project is provided by NIH/NCI 1R01CA141077-01, and The Hope Foundation SWOG0421.Attached Files
Files
Lu2010p10655Mems_2008_21St_Ieee_International_Conference_On_Micro_Electro_Mechanical_Systems_Technical_Digest.pdf
Files
(1.3 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:118b65ba564cd2ca48e245dfb0b15b4d
|
1.3 MB | Preview Download |
Additional details
- Eprint ID
- 19040
- Resolver ID
- CaltechAUTHORS:20100713-150231303
- NIH/National Cancer Institute (NCI)
- 1R01CA141077-01
- The Hope Foundation
- SWOG0421
- Created
-
2010-07-13Created from EPrint's datestamp field
- Updated
-
2021-11-08Created from EPrint's last_modified field
- Series Name
- Proceedings: IEEE Micro Electro Mechanical Systems
- Other Numbering System Name
- INSPEC Accession Number
- Other Numbering System Identifier
- 11246665