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Published June 2010 | Accepted Version
Journal Article Open

Computational Morphodynamics: A Modeling Framework to Understand Plant Growth

Abstract

Computational morphodynamics utilizes computer modeling to understand the development of living organisms over space and time. Results from biological experiments are used to construct accurate and predictive models of growth. These models are then used to make novel predictions that provide further insight into the processes involved, which can be tested experimentally to either confirm or rule out the validity of the computational models. This review highlights two fundamental challenges: (a) to understand the feedback between mechanics of growth and chemical or molecular signaling, and (b) to design models that span and integrate single cell behavior with tissue development. We review different approaches to model plant growth and discuss a variety of model types that can be implemented to demonstrate how the interplay between computational modeling and experimentation can be used to explore the morphodynamics of plant development.

Additional Information

© 2010 by Annual Reviews. Review in Advance first posted online on February 1, 2010. (Changes may still occur before final publication online and in print.) Expected final online publication date for the Annual Review of Plant Biology Volume 61 is April 28, 2010. We thank Bruce Shapiro,Wuxing Li, Kaoru Sugimoto, Pawel Krupinski, and Eric Mjolsness for helpful discussion and comments. We thank Marcus Heisler for providing images. We also acknowledge funding from the Department of Energy (DE-FG02–88ER1387), the National Science Foundation (IOS-0846192), the National Institutes of Health (5R01GM086639), the Gordon and Betty Moore Foundation, and a gift from Peter Cross.We apologize to all those whose research we could not cite here owing to space limitations.

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August 19, 2023
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