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Published April 2009 | public
Journal Article

Gene regulatory networks that control the specification of neural-crest cells in the lamprey

Abstract

The lamprey is the only basal vertebrate in which large-scale gene perturbation analyses are feasible at present. Studies on this unique animal model promise to contribute both to the understanding of the basic neural-crest gene regulatory network architecture, and evolution of the neural crest. In this review, we summarize the currently known regulatory relationships underlying formation of the vertebrate neural crest, and discuss new ways of addressing the many remaining questions using lamprey as an experimental model.

Additional Information

© 2008 Elsevier B.V. Received 14 January 2008. Received in revised form 4 March 2008. Accepted 18 March 2008. Available online 30 March 2008.

Additional details

Created:
August 21, 2023
Modified:
October 19, 2023