Published February 2009
| Supplemental Material
Journal Article
Open
The evolution of hierarchical gene regulatory networks
- Creators
- Erwin, Douglas H.
- Davidson, Eric H.
Chicago
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Abstract
Comparative developmental evidence indicates that reorganizations in developmental gene regulatory networks (GRNs) underlie evolutionary changes in animal morphology, including body plans. We argue here that the nature of the evolutionary alterations that arise from regulatory changes depends on the hierarchical position of the change within a GRN. This concept cannot be accomodated by microevolutionary nor macroevolutionary theory. It will soon be possible to investigate these ideas experimentally, by assessing the effects of GRN changes on morphological evolution.
Additional Information
© 2009 Nature Publishing Group. Published online 13 January 2009. We appreciate the helpful comments from several reviewers. D.H.E. acknowledges support from the NASA Astrobiology Program, and E.H.D. from the National Science Foundation (IOS 0641398).Attached Files
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Additional details
- Eprint ID
- 14706
- Resolver ID
- CaltechAUTHORS:20090728-140404256
- NASA
- NSF
- IOS 0641398
- Created
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2009-08-07Created from EPrint's datestamp field
- Updated
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2021-11-08Created from EPrint's last_modified field