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Published August 20, 2001 | Published
Journal Article Open

Path-Length-Resolved Dynamic Light Scattering: Modeling the Transition From Single to Diffusive Scattering

Abstract

Dynamic light-scattering spectroscopy is used to study Brownian motion within highly scattering samples. The fluctuations of the light field that is backscattered by a suspension of polystyrene microspheres are measured as power spectra by use of low-coherence interferometry to obtain path-length resolution. The data are modeled as the sum of contributions to the detected light weighted by a Poisson probability for the number of events that each component has experienced. By analyzing the broadening of the power spectra as a function of the path length for various sizes of particles, we determine the contribution of multiple scattering to the detected signal as a function of scattering anisotropy.

Additional Information

© 2001 Optical Society of America Received 29 August 2000; revised manuscript received 19 March 2001. We thank Irving Itzkan and Lev Perelman of the MIT Spectroscopy Laboratory for valuable conversations and insights. This study was conducted at the MIT Laser Biomedical Research Center and was supported by grants from the National Institutes of Health (NIH). Adam Wax was supported by a National Research Service Award fellowship grant from the NIH.

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August 21, 2023
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October 16, 2023