Retroviral-Like Element in a Marine Invertebrate
Abstract
Retroviral-like elements (RL elements) include retroviruses and long terminal repeat (LTR)-containing retrotransposons. We report the presence of sea urchin RL elements (termed SURL) in eight species of sea urchins and find that these RL elements belong to several subfamilies. The complete DNA sequence of one SURL element in Tripneustes gratilla is 5266 base pairs long, including 254-nucleotide-long identical long terminal repeats (LTRs). It contains a single open reading frame nearly 4 kilobases long including the gag and pol genes. Comparison of conserved DNA sequences of RL elements from different sea urchin species indicates that active elements have been inserting copies into echinoid genomes for at least 200 million years.
Additional Information
Copyright © 1991 by National Academy of Sciences Contributed by Roy J. Britten, June 17, 1991 We thank R. F. Doolittle and Wen-Hsiung Li for programs and are grateful for a T. gratilla phage A library prepared by Gregory Dolecki at Kewalo Marine Laboratory, Hawaii. This work was supported by the Lucille P. Markey Charitable Trust and the National Institutes of Health. The sequence reported in this paper has been deposited in the GenBank data base (accession no. M75723). The publication costs of this article were defrayed in part by page charge payment. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. §1734 solely to indicate this fact.Attached Files
Published - SPRIpnas91.pdf
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Additional details
- PMCID
- PMC52516
- Eprint ID
- 6818
- Resolver ID
- CaltechAUTHORS:SPRIpnas91
- Lucille P. Markey Charitable Trust
- NIH
- Created
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2006-12-23Created from EPrint's datestamp field
- Updated
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2019-10-02Created from EPrint's last_modified field