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Published February 1, 1971 | public
Journal Article Open

Association of chromosomal RNA with repetitive DNA

Abstract

Chromosomal RNA, which is a component of the chromosomes of higher organisms, and whose participation is required for sequence-specific interaction of chromosomal proteins with chromosomal DNA, occurs in chromosomes bound to DNA. We have found that the DNA sequences to which chromosomal RNA binds are repetitive ones.

Additional Information

© 1971 by the National Academy of Sciences. Communicated December 7, 1970. We wish to acknowledge the helpful counsel of our colleagues John Mayfield and David McConnell. This work was supported in part by a grant from the Goodyear Tire and Rubber Company and in part by U.S. Public Health Service, GM-13762. [Y.M.S. was an] IREX Fellow, 1969-1970.

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