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Published April 1973 | Published
Journal Article Open

Production of Specific Fragments of {varphi}X174 Replicative Form DNA by a Restriction Enzyme from Haemophilus parainfluenzae, Endonuclease HP

Abstract

A restriction endonuclease from Haemophilus parainfluenzae degrades {varphi}X174 replicative form DNA into eight specific fragments, ranging from 1,700 to 150 base pairs and terminated specifically by deoxycytidylic acid.

Additional Information

© 1973 American Society for Microbiology. Received for publication 6 November 1972. This investigation was supported by Public Health Service grant GM 13554 from the National Institute of General Medical Sciences. One of us, P.H.J., is an American Cancer Society postdoctoral research fellow. We would like to thank Lawrence I. Grossman for collaboration in the lambda substrate experiments.

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August 22, 2023
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