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Published June 1969 | Published
Journal Article Open

High sequence diversity in the RNA synthesized at the lampbrush stage of oogenesis

Abstract

Many diverse RNA's are synthesized in the lampbrush stage oocyte of Xenopus, as shown by the presence of different nucleotide sequences in the RNA population. This fact has been established by hybridizing lampbrush stage oocyte RNA with an isolated nonrepetitive fraction of Xenopus DNA.

Additional Information

© 1969 by the National Academy of Sciences. Communicated by Alfred E. Mirsky, March 7, 1969. We are much indebted to Professor Alfred E. Mirsky of this University and to Dr. Roy J. Britten of the Carnegie Institution of Washington for critical discussion and advice throughout this project. We are grateful to Dr. Britten for permitting us the use of his high-pressure pump for shearing DNA as well. In addition, it gives us great pleasure to acknowledge the intelligent and conscientious technical assistance of Miss Maggie Chamberlin. This investigation was supported by American Cancer Society grant E334C and by National Institute of Child Health and Development grant HD-02412-03.

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Created:
August 21, 2023
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October 23, 2023