Published December 1967
| Published
Journal Article
Open
Evidence for a low-molecular-weight collagen precursor
- Creators
- Bekhor, Isaac
- Bavetta, Lucien A.
Abstract
In this communication evidence is presented that collagen-proline hydroxylation occurs on polypeptides of low molecular weight. Thus, the hydroxylation process is initiated prior to the completion of the synthesis of collagen α-chains. The present data rule out the participation of any proteolytic enzymes in obtaining low-molecular-weight polypeptides containing hydroxyproline.
Additional Information
Copyright © 1967 by the National Academy of Sciences. Communicated by James Bonner, September 29, 1967. The authors thank Dr. Samuel Allerton and Mr. Zia Mohseni for their extensive discussion and helpful advice in the preparation of the manuscript. This investigation was supported by U.S. Public Health Service research grants DE-00626-08 and DE-02471-01 and training grant DE-00094-05, National Institute for Dental Research. [L.A.B. was the] [r]ecipient of Career Award 5-K6-DE-6083-02, National Institute for Dental Research.Attached Files
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Additional details
- Eprint ID
- 13091
- Resolver ID
- CaltechAUTHORS:BEKpnas67
- DE-00626-08
- National Institute for Dental Research
- DE-02471-01
- National Institute for Dental Research
- DE-00094-05
- National Institute for Dental Research
- Created
-
2009-01-17Created from EPrint's datestamp field
- Updated
-
2019-10-03Created from EPrint's last_modified field