Published August 2019
| public
Conference Paper
Chemical approaches toward a quantitative, systems-level understanding of protein O-GlcNAcylation signaling networks
- Creators
- Hsieh-Wilson, Linda C.
Abstract
The dynamic posttranslational modification of proteins by O-linked-b-N-acetylglucosamine (O-GlcNAcylation) plays many diverse roles in cellular physiol. and disease. Here we will describe a quant., systems-level approach for studying the function, specificity, and dynamic regulation of O-GlcNAcylation. Elucidation of the signaling networks assocd. with the O-GlcNAc modification provides new insights into its central functions and may reveal new therapeutic approaches to enable its selective modulation.
Additional Information
© 2019 American Chemical Society.Additional details
- Eprint ID
- 97786
- Resolver ID
- CaltechAUTHORS:20190812-135544133
- Created
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2019-08-12Created from EPrint's datestamp field
- Updated
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2019-10-03Created from EPrint's last_modified field