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Published August 2019 | public
Conference Paper

Development of Ni-catalyzed enantioselective reductive cross-coupling reactions

Abstract

Nickel catalyzed cross-coupling reactions have emerged as powerful methods to form C(sp^3)-C(sp^2) and C(sp^3)-C(sp^3) bonds. Ni-catalyzed reductive cross-coupling reactions have proven particularly useful for the cross-coupling of secondary alkyl electrophiles, often providing chiral products as racemic mixts. Recognizing that the ability to render these transformations enantioselective would enhance their impact, our lab. has developed enantioselective Ni-catalyzed reductive cross-coupling reactions of an array of org. electrophiles. This seminar will discuss our recent progress in this area.

Additional Information

© 2019 American Chemical Society.

Additional details

Created:
August 19, 2023
Modified:
October 18, 2023