Published January 1983
| public
Journal Article
The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase
- Creators
- Masters, Jeffrey N.
- Attardi, Giuseppe
Abstract
The nucleotide sequence of the human dihydrofolic acid reductase (DHFR) reading frame has been derived from the analysis of human DHFR cDNA. This sequence and the corresponding amino acid sequence have been compared with those available for the enzyme and its coding segment from other organisms. There is an 89% nucleotide sequence homology between the human DHFR reading frame and the mouse coding sequence. Furthermore, amino acid-sequence homologies of 74%, 81% and 89% has been found between human DHFR and chicken, bovine and mouse DHFR, respectively.
Additional Information
© 1983 Published by Elsevier. Received 13 October 1982, Accepted 15 October 1982. This investigation was supported by NIH grants GM-11726 and T32 GM-07616.Additional details
- Eprint ID
- 95158
- Resolver ID
- CaltechAUTHORS:20190501-163158420
- GM11726
- NIH
- T32 GM07616
- NIH Predoctoral Fellowship
- Created
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2019-05-02Created from EPrint's datestamp field
- Updated
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2021-11-16Created from EPrint's last_modified field