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Published December 1954 | public
Journal Article

On the mechanism of photoreactivation of ultraviolet-inactivated bacteriophage

Abstract

Phage-bacterium complexes of phages T2 and T7 on Escherichia coli B were inactivated by UV, photoreactivated, and then subjected to a second UV irradiation. Photoreactivated complexes had the same sensitivity to UV as reactivated complexes at the same survival level. This result is in agreement with the hypothesis that photoreactivation is effected by a direct reversal of the primary UV damage, rather than by a by-pass mechanism which circumvents the effect of the damage.

Additional Information

© 1954 Elsevier. Received 14 July 1954. Supported by grants-in-aid from the American Cancer Society upon recommendation of the Committee of Growth of the National Research Council and by the Michigan Memorial Phenix Project.

Additional details

Created:
August 19, 2023
Modified:
October 20, 2023