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Published October 11, 1958 | public
Journal Article

Distribution of Proflavin-Induced Mutations in the Genetic Fine Structure

Abstract

We have investigated mutation in the same genetic material induced by proflavin which had been shown by De Mars to be mutagenic in phage. Proflavin is known to interact with deoxyribonucleic acid but, unlike 5-bromouracil, does not appear to become incorporated. Comparison of the distribution of r_II mutations induced by proflavin and by 5-bromouracil shows that these two mutagens act on completely different groups of sites in the genetic structure.

Additional Information

© 1958 Nature Publishing Group.

Additional details

Created:
August 19, 2023
Modified:
October 20, 2023