Resistance to ultraviolet light as an index to the reproduction of bacteriophage
- Creators
- Benzer, S.
Abstract
Infection of a susceptible bacterium by a single phage particle initiates a series of events climaxed, after a time called the latent period, by bursting of the cell and the release of a number (burst size) of replicas of the initial phage. We are here concerned primarily with the intervening process of phage replication which takes place behind the cloak of the cell wall. By prematurely disrupting infected cells, Doermann (1948) found that infective phage replicas are already present well before the time at which the bacterium bursts, i.e., about two-thirds of the way through the latent period. At earlier times, however, no plaque-forming particles are recovered, not even the initial phage. Our attention is, therefore, focused upon this "dark" period, during which the infecting phage must undergo some modification, and the key processes of phage reproduction come to pass.
Additional Information
© 1952 Society of American Bacteriologists. Received for publication July 18, 1951. This investigation was conducted in part at Oak Ridge National Laboratory and continued while the author was at the California Institute of Technology as a Postdoctoral Fellow of the Atomic Energy Commission, and a Fellow in Cancer Research of the American Cancer Society, recommended by the Committee on Growth.Attached Files
Published - 59.full.pdf
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Additional details
- PMCID
- PMC169924
- Eprint ID
- 93214
- Resolver ID
- CaltechAUTHORS:20190225-094335488
- Atomic Energy Commission
- American Cancer Society
- Created
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2019-02-25Created from EPrint's datestamp field
- Updated
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2019-10-03Created from EPrint's last_modified field