Published July 1952
| Published
Journal Article
Open
The crystal structure of hydroxy‐L‐proline. II. Determination and description of the structure
- Creators
- Donohue, Jerry
- Trueblood, Kenneth N.
Abstract
The determination of the crystal structure of hydroxy-L-proline, based on nearly complete data accessible with Cu Kα radiation, confirms the chemical assignment of the relative configurations about the two asymmetric carbon atoms, and leads to the following intramolecular bond distances: carboxyl group: C₁-O₁ = 1•25, C₁-O₂ = 1•27, Cr₁-C₂ = 1•52 Å; pyrrolidine ring: C₂-C₃ = 1•53, C₃-C₄ = 1•50, C₄-C₅ = 1•52, C₅-N = 1.48, N-C₂ = 1•50 Å; hydroxyl group : C₄-O₃ = 1•46 Å. The crystal is held together by a system of hydrogen bonds, with N...O₂ = 2•69, N...O'₂ = 3•17, O₃...O₁ = 2•80 Å. The molecule is in the Zwitterion form. These and various other structural features are discussed.
Additional Information
Received 20 November 1951. First published: July 1952. A preliminary report was presented at the Second Congress of the International Union of CrystaUography at Stockholm in June 1951, and a more detailed description was given at the XIIth International Congress of Pure and Applied Chemistry at New York, September 1951. Aided by a grant from the National Foundation for Infantile Paralysis and from the Lederle Laboratories.Attached Files
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Additional details
- Alternative title
- The crystal structure of hydroxy‐l‐proline. II. Determination and description of the structure
- Eprint ID
- 92952
- Resolver ID
- CaltechAUTHORS:20190215-101956699
- National Foundation for Infantile Paralysis
- Lederle Laboratories
- Created
-
2019-02-15Created from EPrint's datestamp field
- Updated
-
2021-11-16Created from EPrint's last_modified field
- Other Numbering System Name
- Gates and Crellin Laboratories of Chemistry
- Other Numbering System Identifier
- 1627