Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published March 6, 2006 | Published
Book Section - Chapter Open

Optical and mechanical properties in photorefractive crystal based ultrasound-modulated optical tomography

Abstract

Ultrasound-modulated optical tomography (UOT) is a new technique that combines laser light and ultrasound to provide images with good optical contrast and good ultrasound resolution in soft biological tissue. We improve the method proposed by Murray et al to obtain UOT images in thick biological tissues with the use of photorefractive crystal based interferometers. It is found that a long ultrasound burst (on the order of a millisecond) can improve the signal-to-noise ratio dramatically. Also with a long ultrasound burst, the response of the acoustic radiation force impulses can be clearly observed in the UOT signal, which will help to acquire images that record both the optical and mechanical properties of biological soft tissues.

Additional Information

© 2006 Society of Photo-optical Instrumentation Engineers (SPIE). We thank Chul Hong Kim for assistance with experiments measurements. We also appreciate Sava Sakadžić and Roger Zemp for fruitful scientific discussions. This research was supported by the National Institute of Health grant R33 CA094267 and AFOSR FA9550-04-1-0247.

Attached Files

Published - 608616.pdf

Files

608616.pdf
Files (336.7 kB)
Name Size Download all
md5:682f890fa1fdf6a7391f6082259d5a25
336.7 kB Preview Download

Additional details

Created:
August 19, 2023
Modified:
January 14, 2024