Speckle in photoacoustic tomography

Abstract

Photoacoustic tomography is emerging as a promising imaging modality for various biomedical applications. Unlike traditional ultrasound imaging that is plagued by strong speckle artifacts, no obvious speckle has so far been observed in photoacoustic images. We systematically studied the reason for this lack of speckle in photoacoustic tomography based on speckle contrast. Theoretical explanations were validated by simulation. The results here can serve as a basis for developing specific applications, such as tissue characterization, using photoacoustic methods.

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