Published January 1948
| public
Journal Article
Studies on the Denaturation of Antibody. III. Kinetic Aspects of the Inactivation of Diphtheria Antitoxin by Urea
- Creators
- Wright, George G.
- Schomaker, Verner
Abstract
In the present investigation we have studied the effects of pH, urea concentration, and temperature on the inactivation reaction, in order to explore the influence of these factors on its abnormalities. The experimental results are shown to be compatible with a simple kinetic mechanism.
Additional Information
© 1948 American Chemical Society. Received July 2, 1947. This investigation was carried out with the aid of a grant from The Rockefeller Foundation. The authors are indebted to Professor Linus Pauling for suggestions and discussion, to J. Y. Chien for carrying out preliminary experiments on the effect of temperature, and to Sharp and Dohme, Glenolden, Pennsylvania, for supplying the antitoxin and toxinAdditional details
- Eprint ID
- 88185
- DOI
- 10.1021/ja01181a111
- Resolver ID
- CaltechAUTHORS:20180724-121639493
- Rockefeller Foundation
- Created
-
2018-07-24Created from EPrint's datestamp field
- Updated
-
2021-11-16Created from EPrint's last_modified field
- Other Numbering System Name
- Gates and Crellin Laboratories of Chemistry
- Other Numbering System Identifier
- 1072