Published December 2, 1999
| public
Journal Article
Synthesis of Trisubstituted Alkenes via Olefin Cross-Metathesis
- Creators
- Chatterjee, Arnab K.
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Grubbs, Robert H.
Abstract
Trisubstituted alkenes have been prepared for the first time via intermolecular olefin cross-metathesis, using 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ruthenium alkylidene complexes 3a,b in good yields with moderate E selectivity. In addition, protected alcohols near the geminal disubstituted olefin improve reactivity for cross-metathesis.
Additional Information
© 1999 American Chemical Society. Received September 7, 1999. Publication Date (Web): November 2, 1999. Support has been generously provided by the National Institutes of Health. The authors thank Andrew G. Myers, Matthias Scholl, Thomas A. Kirkland, Helen E. Blackwell, and Daniel J. O'Leary for useful discussions and encouragement. The authors also wish to thank Richard Pederson for a generous supply of compound 8.Additional details
- Eprint ID
- 85375
- DOI
- 10.1021/ol991023p
- Resolver ID
- CaltechAUTHORS:20180320-101056334
- NIH
- Created
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2018-04-02Created from EPrint's datestamp field
- Updated
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2021-11-15Created from EPrint's last_modified field