Published July 2017
| Accepted Version
Journal Article
Open
OPA1 and cardiolipin team up for mitochondrial fusion
- Creators
- Liu, Raymond
-
Chan, David C.
Abstract
Fusion between the inner membranes of two mitochondria requires the GTPase optic atrophy 1 (OPA1), but the molecular mechanism is poorly understood. A study now shows that fusion of two liposomes can be performed by OPA1 tethered to just one liposome, through an interaction with the phospholipid cardiolipin on the opposing liposome.
Additional Information
© 2017 Macmillan Publishers Limited, part of Springer Nature. Published online 19 June 2017. The authors declare no competing financial interests.Attached Files
Accepted Version - nihms929351.pdf
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Additional details
- PMCID
- PMC5757513
- Eprint ID
- 78366
- Resolver ID
- CaltechAUTHORS:20170620-091459936
- Created
-
2017-06-20Created from EPrint's datestamp field
- Updated
-
2022-03-25Created from EPrint's last_modified field