Published May 2017
| public
Journal Article
N-ethylformamide dimer. A β-turn model peptide in the gas phase
Abstract
Reported here are CP-FTMW experiments on N-ethylformamide (NEF), previously studied by pure rotational spectroscopy in the gas phase by Hirota and co-workers (2005). Two conformers of the monomer (trans sc and cis ac), the trans-trans sc dimer, and several NEF-water complexes have been detected. (Only trans sc was observed in the earlier experiments.) Of these species, the trans-trans sc dimer is the most interesting since its three-dimensional structure bears a striking resemblance to β-turns in folded peptides. The well-known anti-parallel β-sheet structures would be expected to have near-zero dipole moments and are therefore discriminated against by the CP-FTMW method.
Additional Information
© 2016 Elsevier Inc. Received 1 September 2016, Revised 17 November 2016, Accepted 1 December 2016, Available online 9 December 2016. This work has been supported by NSF (CHE-0960074) and the University of Pittsburgh. The computational resources provided by the Vermont Advanced Computing Core which is supported by NASA (NNX-08AO96G) are gratefully acknowledged.Additional details
- Eprint ID
- 77880
- Resolver ID
- CaltechAUTHORS:20170601-081528774
- CHE-0960074
- NSF
- University of Pittsburgh
- NNX-08AO96G
- NASA
- Created
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2017-06-01Created from EPrint's datestamp field
- Updated
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2021-11-15Created from EPrint's last_modified field