Published September 8, 2004
| Supplemental Material
Journal Article
Open
A Synthetic DNA Walker for Molecular Transport
- Creators
- Shin, Jong-Shik
-
Pierce, Niles A.
Abstract
Inspired by kinesin movement along a microtubule, we demonstrate a processive bipedal DNA walker. Powered by externally controlled DNA fuel strands, the walker locomotes with a 5 nm stride by advancing the trailing foot to the lead at each step. Real-time monitoring of specific bidirectional walker movement is achieved via multiplexed fluorescence quenching.
Additional Information
© 2004 American Chemical Society. Received April 27, 2004; Publication Date (Web): August 17, 2004. We thank the Winfree laboratory at Caltech for the use of their fluorescent gel scanner. The following research support is gratefully acknowledged: DARPA and the Air Force Research Laboratory under agreement F30602-01-2-0561, the Ralph M. Parsons Foundation, and the Charles Lee Powell Foundation.Attached Files
Supplemental Material - ja047543jsi20040702_013316.pdf
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Additional details
- Eprint ID
- 74531
- DOI
- 10.1021/ja047543j
- Resolver ID
- CaltechAUTHORS:20170224-152823096
- Department of Energy (DOE)
- F30602-01-2-0561
- Air Force Research Laboratory
- Ralph M. Parsons Foundation
- Charles Lee Powell Foundation
- Created
-
2017-02-24Created from EPrint's datestamp field
- Updated
-
2021-11-11Created from EPrint's last_modified field