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Published September 13, 2006 | Supplemental Material + Accepted Version
Journal Article Open

A Convergent and Enantioselective Synthesis of (+)-Amurensinine via Selective C−H and C−C Bond Insertion Reactions

Abstract

A convergent and enantioselective synthesis of the natural product amurensinine is described. The synthetic strategy takes advantage of mild and selective C−H and C−C bond insertion reactions, in addition to the palladium-catalyzed aerobic oxidative kinetic resolution recently developed in these laboratories.

Additional Information

© 2006 American Chemical Society. Received 20 July 2006. Published online 17 August 2006. Published in print 1 September 2006. The authors are grateful to the NIH-NIGMS (R01 GM65961-01), NDSEG (predoctoral fellowships to U.K.T. and D.C.E.), NSF (predoctoral fellowship to D.C.E.), A. P. Sloan Foundation, Research Corporation, Bristol-Myers Squibb, Amgen, Merck, Pfizer, Novartis, Lilly, Roche, Abbott, AstraZeneca, and Caltech for financial support.

Attached Files

Accepted Version - nihms-63703.pdf

Supplemental Material - ja0651815si20060804_084023.pdf

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August 19, 2023
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