Published August 11, 2008
| Supplemental Material + Accepted Version
Journal Article
Open
Palladium-Catalyzed Enantioselective Oxidation of Chiral Secondary Alcohols: Access to Both Enantiomeric Series
Abstract
Rapid resolution: A new catalyst system for the oxidative kinetic resolution of secondary alcohols leads to dramatic rate increases. This system allows the use of a diamine to provide access to either enantiomer of a range of alcohols with good selectivity factors (see scheme). This method has been applied to the formal total synthesis of (−)-amurensinine.
Additional Information
© 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received: April 22, 2008; Published online: July 14, 2008. We are grateful to the NIH-NIGMS (R01 GM65961-01), NSF (predoctoral fellowship to D.C.E.), NDSEG (predoctoral fellowship to D.C.E.), Bristol-Myers Squibb and the American Chemical Society (predoctoral fellowship to R.M.T.), EPSRC, and EU.Attached Files
Accepted Version - nihms54998.pdf
Supplemental Material - anie_200801865_sm_miscellaneous_information.pdf
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anie_200801865_sm_miscellaneous_information.pdf
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Additional details
- PMCID
- PMC2790069
- Eprint ID
- 74342
- DOI
- 10.1002/anie.200801865
- Resolver ID
- CaltechAUTHORS:20170215-152617371
- R01GM65961-01
- NIH
- NSF Predoctoral Fellowship
- National Defense Science and Engineering Graduate (NDSEG) Fellowship
- Bristol-Myers Squibb
- American Chemical Society
- Engineering and Physical Sciences Research Council (EPSRC)
- European Union
- Created
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2017-02-15Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field