Published November 2, 2000
| Supplemental Material
Journal Article
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Synthesis of C(3) Benzofuran-Derived Bisaryl Quaternary Centers: Approaches to Diazonamide A
Abstract
Two complementary strategies for the synthesis of the diazonamide A bisaryl quaternary center are described. The first strategy relies upon an extremely facile tandem cyclopropanation/ring-opening sequence, which has proven amenable to chiral catalysis to provide enantioenriched material. The second strategy relies upon a more concise alkylation route ideal for material advancement.
Additional Information
© 2000 American Chemical Society. Received September 11, 2000. Publication Date (Web): October 4, 2000. We are pleased to acknowledge the support of this investigation by Bristol-Myers Squibb, Yamanouchi, Pfizer, and Merck. J.L.W. is a fellow of the Alfred P. Sloan Foundation.Attached Files
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Additional details
- Eprint ID
- 74329
- DOI
- 10.1021/ol006578v
- Resolver ID
- CaltechAUTHORS:20170215-134104826
- Bristol-Myers Squibb
- Yamanouchi
- Pfizer
- Merck
- Alfred P. Sloan Foundation
- Created
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2017-02-15Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field