Millimeter wave-induced changes in membrane properties of leech Retzius neurons
Abstract
This study evaluated a novel method for modulation of neuronal excitability using non-invasive delivery of millimeter waves. Millimeter waves at 60 GHz and incident power density of 100-600 μW/cm^2 were applied to three intact segmental ganglia of the adult leach, and intracellular neuronal activity was recorded from the Retzius neurons using intracellular glass electrode. Transient dosedependent increase in the plasma membrane permeability was observed. In addition, in one of the examined neurons, a decrease in the neuronal firing rate was also evident. The results provide strong evidence for the feasibility of modulating neuronal excitability using non-invasive delivery of millimeter waves, and will be explored further for applications in basic neuroscience and treatment of neurological disorders.
Additional Information
© 2011 SPIE Society of Photo-Optical Instrumentation Engineers.Attached Files
Published - 788356_1.pdf
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Additional details
- Eprint ID
- 71631
- Resolver ID
- CaltechAUTHORS:20161031-141459277
- Created
-
2016-11-01Created from EPrint's datestamp field
- Updated
-
2021-11-11Created from EPrint's last_modified field
- Series Name
- Proceedings of SPIE
- Series Volume or Issue Number
- 7883