Published July 2006
| public
Journal Article
Significantly accelerated osteoblast cell growth on aligned TiO_2 nanotubes
Abstract
Vertically aligned yet laterally spaced nanoscale TiO2 nanotubes have been grown on Ti by anodization, and the growth of MC3T3-E1 osteoblast cells on such nanotubes has been investigated. The adhesion/propagation of the osteoblast is substantially improved by the topography of the TiO_2 nanotubes with the filopodia of growing cells actually going into the nanotube pores, producing an interlocked cell structure. The presence of the nanotube structure induced a significant acceleration in the growth rate of osteoblast cells by as much as ∼300–400%.
Additional Information
© 2006 Wiley Periodicals, Inc. Received 12 August 2005; revised 8 December 2005; accepted 22 December 2005; Published online 6 April 2006. The authors thank J. Blackwell at UC San Diego for helpful discussions and assistance in experiments.Additional details
- Eprint ID
- 70850
- Resolver ID
- CaltechAUTHORS:20161005-073226212
- Created
-
2016-10-05Created from EPrint's datestamp field
- Updated
-
2021-11-11Created from EPrint's last_modified field