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Published 1980 | public
Book Section - Chapter

Picosecond Torsional Dynamics of DNA

Abstract

Studies of the structure and conformational dynamics of DNA are central to an understanding of its biological function. Although the long-range segmental motions of the DNA helix have been well characterized by a variety of physical techniques [1], very little is known about the more rapid internal motions in DNA [2–4]. Our objective here is to investigate the torsional (twisting) dynamics of DNA using the techniques of picosecond time-dependent fluorescence depolarization, and to compare the results with the predictions of the elastic model presented by BARKLEY and ZIMM [5].

Additional Information

© 1980 Springer. This work was supported in part by the National Science Foundation under grant CBE79-05683. AHZ is the recipient of an Alfred P. Sloan Foundation Fellowship and a Camille and Henry Dreyfus Foundation teacher- scholar award. This is Contribution No. 6263 from the Division of Chemistry and Chemical Engineering of the California Institute of Technology.

Additional details

Created:
August 19, 2023
Modified:
January 13, 2024