Published March 16, 2009
| Accepted Version
Journal Article
Open
Micromachined "side-viewing" optical sensor probe for detection of esophageal cancers
Abstract
In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with "side viewing" capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates and source/collection fibers to achieve 45° light incidence and collection of spatially resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for differentiation of cancerous tissues from normal ones.
Additional Information
© 2008 Elsevier B.V. Received 6 May 2008; Received in revised form 25 October 2008; Accepted 7 November 2008; Available online 25 November 2008. This project is partially supported by National Institutes of Health under contract R01 CA106728.Attached Files
Accepted Version - nihms117654.pdf
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nihms117654.pdf
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Additional details
- PMCID
- PMC4286192
- Eprint ID
- 70492
- DOI
- 10.1016/j.sna.2008.11.008
- Resolver ID
- CaltechAUTHORS:20160921-092710571
- R01 CA106728
- NIH
- Created
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2016-09-29Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field