Published January 2017
| Accepted Version
Journal Article
Open
Electrophilic Rh^I catalysts for arene H/D exchange in acidic media: evidence for an electrophilic aromatic substitution mechanism
Abstract
A series of new rhodium (I) complexes supported by bidentate nitrogen-donor ligands with varying electronic and steric properties were synthesized in situ and evaluated for catalytic arene C−H/D activation. In trifluoroacetic acid (HTFA), these complexes are proposed to mediate H/D exchange of arene C−H/D bonds by an electrophilic aromatic substitution mechanism that involves Rh-mediated activation of HTFA (or DTFA). DFT calculations support the proposed pathway for the H/D exchange reactions.
Additional Information
© 2016 Elsevier. Received 27 June 2016, Revised 23 July 2016, Accepted 25 July 2016, Available online 1 August 2016. The authors acknowledge the National Science Foundation (CHE-1465145, TBG; NSF CHE-1214158, WAG) for financial support. M.S.W-G. acknowledges support from AES for a graduate student fellowship, the Jefferson Scholars Foundation for a dissertation year fellowship and Junqi Chen for assistance with an experimental procedure.Attached Files
Accepted Version - SUBMITTED_REVISION.pdf
Files
SUBMITTED_REVISION.pdf
Files
(1.4 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:b53b8042b9084af1ba213d0c5c42d84f
|
1.4 MB | Preview Download |
Additional details
- Eprint ID
- 69418
- Resolver ID
- CaltechAUTHORS:20160803-142334974
- CHE-1465145
- NSF
- CHE-1214158
- NSF
- AES Graduate Student Fellowship
- Jefferson Scholars Foundation
- Created
-
2016-08-03Created from EPrint's datestamp field
- Updated
-
2021-11-11Created from EPrint's last_modified field