Published October 28, 1970
| public
Journal Article
Structure of the DNA of bacteriophage φX174. VII. Methylation
Abstract
The only methylated base present in φX174 DNA has been found to be 5-methylcytosine. The number of methyl residues per molecule of φX DNA is estimated to be not more than one. This 5-methylcytosine appears in the φX174 DNA in a non-random distribution; it is found almost exclusively in the dinucleotide fraction of the pyrimidine isopliths, and as judged by its electrophoretic characteristics, the sequence of the 5-methylcytosine containing dinucleotide is either p-m^5C-p-T-p or p-T-p-m^5C-p.
Additional Information
© 1970 Elsevier Ltd. Received 30 March 1970. This research was supported in part by a grant from the U.S. Public Health Service GM-13554 and a postdoctoral research fellowship 1F05-TW-1348 to one of us (A.R.). The participation of Dr Rolf Knippers in the very early stages of this work and the skillful technical assistance of Miss Alma Shafer are very much appreciated.Additional details
- Eprint ID
- 69399
- Resolver ID
- CaltechAUTHORS:20160802-150703422
- GM-13554
- U.S. Public Health Service (USPHS)
- 1F05-TW-1348-01
- NIH Postdoctoral Fellowship
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2016-08-03Created from EPrint's datestamp field
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2021-11-11Created from EPrint's last_modified field