Rhesus monkey brain imaging through intact skull with thermoacoustic tomography
- Creators
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Xu, Yuan
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Wang, Lihong V.
Abstract
Two-dimensional microwave-induced thermoacoustic tomography (TAT) is applied to imaging the Rhesus monkey brain through the intact skull. To reduce the wavefront distortion caused by the skull, only the low-frequency components of the thermoacoustic signals (< 1 MHz) are used to reconstruct the TAT images. The methods of signal processing and image reconstruction are validated by imaging a lamb kidney. The resolution of the system is found to be 4 mm when we image a 1-month-old monkey head containing inserted needles. We also image the coronal and axial sections of a 7-month-old monkey head. Brain features that are 3 cm deep in the head are imaged clearly. Our results demonstrate that TAT has potential for use in portable, cost-effective imagers for pediatric brains.
Additional Information
© 2006 IEEE. Manuscript received December 22, 2004; accepted August 9, 2005. The work is sponsored in part by the U.S. Army Medical Research and Material Command Grant No. DAMD17-00-1-0455, the National Institutes of Health Grant No. R01 NS46214, and the Texas Higher Education Coordinating Board Grant No. ARP 000512-0063-2001. We would like to thank the California Primate Research Center for providing samples for the experiments, and G. Stoica for his advice and help in dissecting the heads.Attached Files
Published - 01610562.pdf
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Additional details
- Eprint ID
- 68972
- Resolver ID
- CaltechAUTHORS:20160711-152157636
- DAMD17-00-1-0455
- Army Medical Research and Materiel Command
- R01 NS46214
- NIH
- ARP 000512-0063-2001
- Texas Higher Education Coordinating Board
- Created
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2016-07-28Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field